Antipsychotic Use In Elderly People With Alzheimer's Leads To Large Increase In Mortality

From Medical News Today:

There is a large increased long-term risk of mortality in patients with
Alzheimer's disease (AD) who are prescribed antipsychotic medication....

In total, 165 patients were randomised and of these, 128 started
treatment - 64 on antipsychotics, 64 on placebo. At 12 months, there
was 70% survival in the antipsychotic group compared with 77% in
placebo. However, longer term follow-up revealed bigger differences in
survival. At 2 years, survival was 46% in the antipsychotic group and
71% in the placebo group, and at 36 months the difference was even
greater: 30% antipsychotic versus 59% placebo. Overall, across the
whole study period, the risk of death was 42% lower in the placebo
group than in the antipsychotic group....

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