News, Notes, and Opinions from Michigan about the progress of choice-based long term care
Wednesday, June 11, 2008
Bright Lighting Could Improve Dementia Symptoms In Elderly
Norman DeLisle, MDRC
"With Liberty and Access for All!"
GrandCentral: 517-589-4081
MDRC Website: http://www.copower.org/
LTC Blog: http://ltcreform.blogspot.com/
Recovery: http://therecoveringlife.blogspot.com/
Change: http://prosynergypsc.blogspot.com/
Wednesday, June 4, 2008
2008 Alzheimer's Disease Facts and Figures
10 million baby boomers will develop Alzheimer's disease.
43 pages.
Norman DeLisle, MDRC
"With Liberty and Access for All!"
GrandCentral: 517-589-4081
MDRC Website: http://www.copower.org/
LTC Blog: http://ltcreform.blogspot.com/
Recovery: http://therecoveringlife.blogspot.com/
Change: http://prosynergypsc.blogspot.com/
Tuesday, January 22, 2008
Engaging People with Early Stage Alzheimer's Disease in the Work of the Alzheimer Society
Drawing from related literature, the experiences of people with the disease, Alzheimer Society staff, and key informants, this report examines the factors that influence individuals to volunteer and the barriers that may limit their participation.
http://www.alzheimer.ca/docs/EarlyStagesEng.pdf
Thursday, January 10, 2008
Reversal Of Alzheimer's Symptoms Within Minutes In Human Study
This new study highlights the importance of certain soluble proteins, called cytokines, in Alzheimer’s disease. The study focuses on one of these cytokines, tumor necrosis factor-alpha(TNF), a critical component of the brain’s immune system. Normally, TNF finely regulates the transmission of neural impulses in the brain. The authors hypothesized that elevated levels of TNF in Alzheimer’s disease interfere with this regulation. To reduce elevated TNF, the authors gave patients an injection of an anti-TNF therapeutic called etanercept. Excess TNF-alpha has been documented in the cerebrospinal fluid of patients with Alzheimer’s.
The new study documents a dramatic and unprecedented therapeutic effect in an Alzheimer’s patient: improvement within minutes following delivery of perispinal etanercept, which is etanercept given by injection in the spine. Etanercept (trade name Enbrel) binds and inactivates excess TNF. Etanercept is FDA approved to treat a number of immune-mediated disorders and is used off label in the study.
The use of anti-TNF therapeutics as a new treatment choice for many diseases, such as rheumatoid arthritis and potentially even Alzheimer’s, was recently chosen as one of the top 10 health stories of 2007 by the Harvard Health Letter.